Precision health in Alzheimer disease: Risk assessment-based strategies


Institute of Global Health & Human Ecology

Description or Abstract

Alzheimer disease (AD) is a chronic neurodegenerative condition that affects an individual's cognitive function over an extended period. Treatment and prevention for AD have long been sought after; however, no strategy has yet been successful, as individuals with cognitive impairment usually present to the clinic when they have reached an advanced stage of the disease. The disease is progressive and multifactorial in its pathogenesis. Precision medicine (PM) is the new era of medicine comprising a holistic approach in dealing with diseases. With scientific innovations, PM has improved our disease knowledge, altered diagnoses and therapy approaches resulting in a more precise, predictive, preventative and personalized patient care. PM in AD focuses, among other things, on stratifying individuals according to their risk factors of developing the disease and applying preventative strategies and personalized treatment approaches for a better outcome. In this mini-review, we have focused on a few modifiable and non-modifiable risk factors and presented recommendations for future consideration to implement.


Precision Medicine, Alzheimer's Disease, Public Health, Risk Assessment, Prevention


Original source citation:

Azar, J, Salama, M, Chidambaram, SB, Al‐Balushi, B, Essa, MM, Qoronfleh, MW. Precision health in Alzheimer disease: Risk assessment‐based strategies. Precision Medical Sciences. 2021; 1– 17. https://doi.org/10.1002/prm2.12036

Faculty Advisor

Mohamed Salama


GHHE 000/5420

Content Type




First Page


Last Page


Original Publication Title

Precision Medical Sciences


Wiley Online Library

Publisher Location

New Jersey