Linagliptin: A comprehensive profile

Funding Sponsor

American University in Cairo

Author's Department

Chemistry Department

Second Author's Department

Chemistry Department

Third Author's Department

Chemistry Department

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https://doi.org/10.1016/bs.podrm.2024.10.001

All Authors

Mohamed Fawzy Kabil Jude Majed Lababidi Hassan Mohamed El Said Azzazy

Document Type

Research Article

Publication Title

Profiles of Drug Substances Excipients and Related Methodology

Publication Date

1-1-2025

doi

10.1016/bs.podrm.2024.10.001

Abstract

Linagliptin (LINA) is the first dipeptidyl peptidase IV (DPP-IV) inhibitor that could be administered orally to control hyperglycemia. It is indicated for controlling adult blood sugar levels that are diagnosed with diabetes mellitus type II. The current chapter provides a complete review of LINA including nomenclature, physiochemical characteristics, synthesis, and thermal analysis. Additionally, different analytical techniques used for quantitative and qualitative determination of LINA are presented.

First Page

97

Last Page

123

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