Interactions between dietary flavonoids and the gut microbiome: A comprehensive review
Find in your Library
https://doi.org/10.1017/S0007114521003627
Document Type
Research Article
Publication Title
British Journal of Nutrition
Publication Date
1-1-2021
doi
10.1017/S0007114521003627
Abstract
Flavonoids are natural polyphenol secondary metabolites that are widely produced in planta. Flavonoids are ubiquities in human dietary intake and exhibit a myriad of health benefits. Flavonoids-induced biological activities are strongly influenced by their in-situ availability in the human GI tract, as well as the levels of which are modulated by interaction with the gut bacteria. As such, assessing flavonoids-microbiome interactions is considered a key to understand their physiological activities. Here, we review the interaction between the various classes of dietary flavonoids (flavonols, flavones, flavanones, isoflavones, flavan-3-ols, and anthocyanins) and gut microbiota. We aim to provide a holistic overview of the nature and identity of flavonoids on diet, and highlight how flavonoids chemical structure, metabolism, and impact on humans and their microbiomes are interconnected. Emphasis is placed on how flavonoids and their biotransformation products affect gut microbiota population, influence gut homeostasis, and induce measurable physiological changes and biological benefits.
Recommended Citation
APA Citation
Baky, M.
Elshahed, M.
Wessjohann, L.
&
Farag, M.
(2021). Interactions between dietary flavonoids and the gut microbiome: A comprehensive review. British Journal of Nutrition,
10.1017/S0007114521003627
https://fount.aucegypt.edu/faculty_journal_articles/2468
MLA Citation
Baky, Mostafa H., et al.
"Interactions between dietary flavonoids and the gut microbiome: A comprehensive review." British Journal of Nutrition, 2021,
https://fount.aucegypt.edu/faculty_journal_articles/2468