Nanoparticle-based detection of cancer-associated RNA
Author's Department
Chemistry Department
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https://doi.org/10.1002/wnan.1266
Document Type
Research Article
Publication Title
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology
Publication Date
1-1-2014
doi
10.1002/wnan.1266
Abstract
According to the World Health Organization (WHO), cancer cases are expected to increase globally by 57% over the coming two decades. A critical factor in the management of cancer is early detection using highly sensitive diagnostic techniques. RNAs play a vital role in cancer pathogenesis. The detection of aberrant and/or abnormally expressed RNA has been reported in several cancers. Nanoparticle-based assays have been shown to have enhanced specificity and sensitivity as compared with conventional methods. In addition, nanoparticles have enabled the development of new diagnostic strategies. This review covers nanoparticle-based techniques used for the detection of mRNA and micro-RNA associated to different cancers. © 2014 Wiley Periodicals, Inc.
First Page
384
Last Page
397
Recommended Citation
APA Citation
Elbehery, A.
&
Azzazy, H. M.
(2014). Nanoparticle-based detection of cancer-associated RNA. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 6(4), 384–397.
10.1002/wnan.1266
https://fount.aucegypt.edu/faculty_journal_articles/1825
MLA Citation
Elbehery, Ali H.A., et al.
"Nanoparticle-based detection of cancer-associated RNA." Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, vol. 6,no. 4, 2014, pp. 384–397.
https://fount.aucegypt.edu/faculty_journal_articles/1825