Title

Pectin in diet: Interactions with the human microbiome, role in gut homeostasis, and nutrient-drug interactions

Funding Number

2016423

Funding Sponsor

National Science Foundation

Find in your Library

https://doi.org/10.1016/j.carbpol.2020.117388

Document Type

Research Article

Publication Title

Carbohydrate Polymers

Publication Date

3-1-2021

doi

10.1016/j.carbpol.2020.117388

Abstract

Pectins are a part of daily diet as well as food additives that are indigestible polysaccharides by human enzymes, however, they can be easily degraded by gut bacteria with the production of short chain fatty acids (SCFAs). Knowledge of pectin gut homeostasis and further how pectin affect gut bacterial communities is insufficient and limited. This review focuses on providing the whole story of how pectin functions as prebiotics in the gut. Understanding the interplay between functional and immunological responses inside animal or human gut as influenced by pectin in diets is provided. The interaction between pectin and gut microbiota is presented from both sides, in terms of how pectin affects gut microbiome and or the fermentation products produced in response by gut bacteria. This knowledge can be used to define preferred dietary pectins, targeting beneficial bacteria, and favoring balanced microbiota communities in the gut to maximize pectins’ health benefits.

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